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Part of the UCL–French Embassy Conférence-Débat Series 2013
Nanoparticles have unique properties that could revolutionise medicine, with applications in diagnosis, therapy, regenerative medicine and more. Through two complementary short lectures, Dr Florence Gazeau (CNRS, University Paris Diderot) and Professor Quentin Pankhurst (UCL Institute of Biomedical Engineering) will discuss this potential, focusing on the work of their groups on both sides of the Channel on nanomagnetism.
This is the last in a series of four lectures, bringing together experts from UCL and France to share and compare perspectives on engineering for human well-being, followed by an opportunity to ask questions, and a reception to discuss the ideas presented.
NANOMAGNETISM FOR NANOMEDICINE
The scale of nano-objects is pretty much that of subcellular features of the body, making medicine and health tempting applications for nanotechnology. Nanodevices have unique physical properties, which can be imported into living cells and organisms, opening up revolutionary medical applications. This lecture will introduce how the very specific responses and behaviour ofnanoparticles can be potent effectors for diagnostic, therapy and regenerative medicine. We will focus particularly on nanomagnets, which combine multiple functionalities useful for medical imaging and targeted cancer treatments as well as cell-based therapy. Safety issues around nanotoxicity and the eventual fate of nanoparticles in the organism will be also discussed.
Biography of Dr Florence Gazeau
Florence Gazeau completed her Ph.D. degree in physics in 1997, focusing on the magnetic and hydrodynamic properties of ferrofluids. She is a senior scientist in CNRS, in the group NanoBioMagnetism group of the laboratory Matière et Systèmes Complexes (MSC) at the University Paris Diderot. She also belongs to the French Observatory for Micro and Nanotechnology (OMNT). Her main research interests are within nanomagnetism and nanomedicine: interaction of nanoparticles with the biological environment, Magnetic Resonance Imaging of cell migration, nanoparticle-mediated hyperthermia, and cell manipulation for cell therapy. She recently developed multiscale nanometrology methods to evaluate the biotransformation and fate of nanomaterials in organisms.
Biography of Professor Quentin Pankhurst
Quentin Pankhurst runs research programmes as Director of the Davy-Faraday Research Laboratory at the Royal Institution in bio- and nanomagnetism aimed at making practical advances in the use of magnetic nanoparticles in healthcare. These include medical imaging devices, targeted regenerative medicine, molecular imaging microscopy for living cells, and the development of multi-functional nanoparticles for therapy and diagnostics. Pankhurst is also a founder and the current CTO of Endomagnetics Ltd, a spin-out company which in 2010 gained a CE mark for, and started selling, the SentiMag – an intra-operative medical device for breast cancer surgery. In 2012 he was apporinted Director of the UCL Institute of Biomedical Engineering, an organisation which brings together expertise in a diverse selection of research for biomedical purposes at UCL.